Organosulfur Compounds
Medchemexpress LLC CB2 modulator 1 | 666261-80-9 | 99.8% | 380.36 | C18H19F3N4O2 | 5 MG
CB2 modulator 1 is a potent small-molecule modulator of the cannabinoid receptor CB2 intended for research use. It has reported activity relevant to immune disorders, inflammation, osteoporosis, and renal ischemia. Supplied as a high-purity solid for in vitro and exploratory studies; follow appropriate safety and regulatory guidance.
- Acts on cannabinoid receptor CB2.
- Reported activity in immune disorders, inflammation, osteoporosis, and renal ischemia.
- CAS number 666261-80-9.
- Molecular formula C18H19F3N4O2.
- Molecular weight 380.36 g/mol.
- Purity 99.75% (reported).
- Available in small pack sizes for screening, e.g., 5 mg.
- Intended for research use only; follow appropriate safety guidance.
Medchemexpress LLC Bithionol (sulfoxide) | 844-26-8 | 99.0% | 372.05 | 100 MG
Bithionol sulfoxide is an anti-infection agent specifically used for parasites. It exhibits mutagenic activity. This compound is utilized in research concerning parasitic infections such as paragonimiasis, flukes, and cestodes infection.
- Functions as an anti-infection agent targeting parasites.
- Observed to possess mutagenic activity.
- Suitable for research applications related to parasitic infections.
- Can be used for research into parasitic infections including paragonimiasis, flukes, and cestodes infection.
Medchemexpress LLC Sulindac-d3 | 99.4% | C20H14D3FO3S | 1 MG
Sulindac-d3 is a deuterium labeled variant of Sulindac, a non-steroidal antiinflammatory agent. It functions as a COX-2 inhibitor, effectively inhibiting the overexpression of COX-2.
- Deuterium labeled compound
- Acts as a COX-2 inhibitor
- Inhibits overexpression of COX-2
- Used in research areas such as COX, Autophagy, Inflammation/Immunology, and Cancer
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 g/mol | C17H16N4S | 10 MG
Nur77 modulator 3 is a small-molecule research compound that binds nuclear receptor Nur77 (NR4A1) and modulates its activity. It has been reported to inhibit TGF-β1-induced α-SMA and COLA1 expression and to reduce hepatic stellate cell activation and extracellular matrix deposition. Technical identifiers include CAS 2097787-75-0, formula C17H16N4S, molecular weight 308.40 g/mol, and purity 99.01%.
- Modulates Nur77 activity in cellular and in vivo models.
- Inhibits TGF-β1-induced α-SMA and COLA1 expression.
- High purity (99.01%) suitable for biochemical and cell-based assays.
- Supplied in small quantities appropriate for assay development and pilot studies.
Medchemexpress LLC A1AT modulator 1 | 2406205-61-4 | 99.8% | 370.42 | C21H23FN2O3 | 5 MG
A1AT modulator 1 is a research-grade small molecule inhibitor used to study Z α1-antitrypsin polymerization and related biochemical pathways. The compound is a solid (white to off-white) with molecular formula C21H23FN2O3 and molecular weight 370.42. It is provided for laboratory research use with storage recommendations for both powder and solution to maintain stability.
- Potent inhibitor of Z α1-antitrypsin polymerization (pIC50 = 8.3).
- High analytical purity (99.77%).
- Solid, white to off-white appearance suitable for handling in lab settings.
- Stable when stored under recommended conditions (powder: -20°C or 4°C; in solvent: -80°C or -20°C).
- Provided in small-quantity packaging appropriate for research assays.
Medchemexpress LLC MRGPRX4 modulator-1 (compound 31-2) | 2492596-61-7 | 98.1% | 359.73 g·mol⁻¹ | C16H13ClF3NO3 | 5 MG
MRGPRX4 modulator-1 is a small-molecule antagonist of the Mas-related G-protein coupled receptor X4 (MRGPRX4) intended for in vitro and preclinical research into itch, pain, and immune-related pathways. The compound is supplied as a solid and as a DMSO solution and is characterized by potency suitable for biochemical and cellular assays.
- Antagonist activity with IC50 <100 nM for MRGPRX4.
- Molecular formula C16H13ClF3NO3 and molecular weight 359.73 g·mol⁻¹.
- High purity around 98% as reported in documentation.
- Available as solid milligram quantities and as a 10 mM solution in DMSO.
- Appearance white to light yellow solid.
- Storage: powder at -20°C (long term) or 4°C (short term); in solvent at -80°C or -20°C for shorter periods.
- Intended for biochemical and cellular research into itch, pain, and immune pathways.
Medchemexpress LLC Acetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]- | 1050506-75-6 | 98.1% | C19H16ClNO4S | 1 ML
GPR120 modulator 1 is a G protein coupled receptor 120 (GPR120) modulator. This compound, extracted from patent US8394841B2 (compound example F1), is suitable for research into diseases linked to abnormal or deregulated GPR120, including diabetes.
- Modulates G protein coupled receptor 120 (GPR120)
- Supports research on diseases linked to GPR120 deregulation, such as diabetes
- Purity of 98.1% (HPLC)
- White to off-white solid appearance
- Chemical formula C19H16ClNO4S
Selleck Chemical LLC Sulindac S2007-1g
Sulindac(MK-231) is a non-steroidal COX inhibitor which potently inhibits prostaglandin synthesis used in the treatment of acute or chronic inflammatory conditions
Apexbio Technology LLC Sulindac 38194-50-2 100mg
Sulindac (CAS 38194-50-2) is a nonsteroidal anti-inflammatory drug that functions as a prodrug and is metabolized in vivo to pharmacologically active sulindac sulfide and sulindac sulfone Sulindac sulfide acts as a cyclooxygenase inhibitor and modulates intracellular signaling pathways including the repression of ras activity Sulindac sulfone possesses antitumor properties independent of cyclooxygenase inhibition Due to these distinct metabolites and their activities sulindac is utilized in biomedical research for studying inflammatory processes cyclooxygenase-mediated pathways and the chemopreventive mechanisms involved in tumorigenesis
Medchemexpress LLC Triclabendazole sulfoxide | 100648-13-3 | 98.78% | 375.66 | 50 MG
Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole and exhibits anti-parasite effects. It can also inhibit the membrane transporter ABCG2/BCRP.
- Exhibits anti-parasite effects.
- Can inhibit membrane transporter ABCG2/BCRP.
- Available in different quantities to suit research needs.
- Purity of 98.78%.
- Multiple related antibodies and small molecules are also listed, indicating its use in various research areas such as anti-infection, membrane transporter/ion channel, protein tyrosine kinase/RTK, and parasitic infection.
Medchemexpress LLC N'-(3-acetylphenyl)-N-(3-(2-methoxyethyl)-2,4-dioxo-1-(2-(piperidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinazolin | 2946701-09-1 | 99.3% | 507.58 g/mol | C27H33N5O5 | 10 MG
COP1-ATGL modulator 1 is an orally active small-molecule research reagent that modulates the COP1-ATGL pathway. It increases ATGL protein expression, reduces ATGL and COP1 ubiquitination, and diminishes lipid accumulation in hepatocytes at nanomolar concentrations. Supplied as a white to off-white solid with high purity and defined storage recommendations for powder and solution.
- Orally active modulator of COP1-ATGL signaling.
- Increases ATGL protein expression at nanomolar concentrations.
- Reduces ATGL and COP1 ubiquitination in cellular assays.
- High purity suitable for research applications.
- Stable solid with recommended low-temperature storage.